HAWE Andrea;DEL RIO Alessandra;Ares Trading S.A.;RINALDI Gianluca;FREITAG Angelika
发明人:
RINALDI Gianluca,DEL RIO Alessandra,FREITAG Angelika,HAWE Andrea
申请号:
IL25287117
公开号:
IL252871D0
申请日:
2017.06.13
申请国别(地区):
IL
年份:
2017
代理人:
摘要:
The present invention relates to novel liquid protein formulations, particularly arginine-free liquid pharmaceutical compositions of etanercept. The invention employs particular combinations and classes of buffer systems, tonicifiers, and sugar stabilisers, optionally alongside polar ionisable amino acids (e.g. aspartic acid, glutamic acid, histidine, and lysine), to afford a viable and storable drug product.