PRABHU, KUMBLE SANDEEP,PAULSON, ROBERT FRANK,HEGDE, SHAILAJA,KAUSHAL, NAVEEN,GANDHI, UJJAWAL HITENDRA
申请号：
CA2839102
公开号：
CA2839102A1
申请日:
2012.06.29
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Compositions, kits and methods for treating leukemia in a subject (e.g., human) include a first anti-cancer drug consisting of: ?12-prostaglandin J3 or a derivative thereof, or a prostaglandin D receptor (DP) agonist. The compositions may further include a second anti-cancer drug. ?12-prostaglandin J3 is a stable metabolite of omega-3 fatty acid, eicosapentaenoic acid (EPA), and was discovered to have anti-leukemic properties. The compositions, kits and methods may be particularly useful for treating human subjects who are resistant to one or more anti-cancer drugs.
