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Indonesian Derivatives as Anti-Dengue Virus Replication Inhibitors
专利权人:
JANSSEN PHARMACEUTICALS, INC.;KATHOLIEKE UNIVERSITEIT LEUVEN
发明人:
申请号:
ARP180100777
公开号:
AR111315A1
申请日:
2018.03.28
申请国别(地区):
AR
年份:
2019
代理人:
摘要:
1. This paper deals with substituted Indian forest derivatives.A The use of these compounds in the prevention or treatment of dengue virus infection and the use of these compounds as medicines;Best of allDrugs used to treat or prevent dengue virus infection. The present document also deals with compound drugs or preparations of these compounds.1. Composing or composing for medicinal purposes,It is best used to prevent or treat viral infections caused by dengue fever. This paper also deals with the preparation process of compounds. Claim 1: A formula compound (1),Including any form of chemical isomerization stereo,Among them, R1 is fluorescence.R2 ES-CH83228CH8322; CH83228OH,R3 is trifluoromethyl.R830808 is hydrogen.Or R1 is fluorescence,R2 ES-CH83228CH8322; CH83228OH,R3 is trifluoromethyl.R830808 is Metoxi,Or R1 is fluorescence,R2 ES-CH83228CH8322; CH83228OH,R3 is iodine trifluoride XI.R830808 is hydrogen.Or R1 is chlorine.R2 ES-CH83228CH8322; CH83228OH,R3 is trifluoromethyl.R830808 is hydrogen.Or R1 is chlorine.R2 ES-CH83228CH8322; CH83228OH,R3 is trifluoromethyl.R830808 is Metoxi,Or R1 is chlorine.R2 ES-CH83228CH8322; CH83228OH,R3 is iodine trifluoride XI.R830808 is hydrogen.Or R1 is chlorine.R2 ES-(Ch832223)8333; COoh,R3 is trifluoromethyl.R830808 is hydrogen.Or R1 is chlorine.R2 ES-(Ch832223)8333; COoh,R3 is trifluoromethyl.R830808 is Metoxi,Or R1 is chlorine.R2 ES-(Ch832223)8333; COoh,R3 is iodine trifluoride XI.R830808 is hydrogen.Or saltAcceptable polymorphine in solution or medicine.La presente se refiere a derivados de indolina sustituidos, a métodos para prevenir o tratar infecciones virales por dengue mediante el uso de dichos compuestos y también se refiere a dichos compuestos para su uso como medicamento, más preferentemente, para su uso como medicamento para tratar o prevenir infecciones virales por dengue. La presente se refiere además a composiciones farmacéuticas o preparados combinados de los compuestos, a las composiciones o preparados para su uso
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