Crystalline forms of temozolomide and the method for preparing same

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专利权人:

Jiangsu Tasly Diyi Pharmaceutical Co.; Ltd.

发明人:

Guocheng Wang,Wenzheng Liu,Yuzhe Gao,Hailong Yang,Qingwei Hou,Yu Zhang

申请号：

US15033242

公开号：

US09714250B2

申请日:

2014.10.28

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Provided in the present invention are a new method for preparing the crystalline forms of Temozolomide and three types of crystalline form of Temozolomide by the method. Said method comprises the following steps: a Temozolomide is dissolved into dimethyl sulphoxide, a second organic solvent is added for recrystallization to prepare the crystalline forms of Temozolomide, wherein the second organic solvent is an alcohol, a ketone, a halohydrocarbon or an ester.

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