RAO, Ashwin, U.,MCKITTRICK, Brian Alexander,LOMBARDO, Matthew,HICKS, Jacqueline, D.,MCCRACKEN, Amy Bittner,CHU, Hong Dong,SO, Sung-Sau,ORTH, Peter,WU, Zhicai,LAN, Ping,DEBENHAM, John, S.,WHITEHEAD, Br
申请号:
EP17872824
公开号:
EP3541375A4
申请日:
2017.11.13
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIIa inhibitors.