Jacqueline D. Hicks,Brian Alexander McKittrick,Brent R. Whitehead,Matthew Lombardo,Xiaoqing Han,Jerry A. Taylor,Hong Dong Chu,Sung-Sau So,Peter Orth,Zhicai Wu
申请号:
US16461825
公开号:
US20200262831A1
申请日:
2017.11.13
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIIa inhibitors.