Hong Dong CHU;Peter ORTH;Brian Alexander MCKITTRICK;Amy Bittner MCCRACKEN;Jacqueline D. HICKS;Sung-Sau SO;John S. DEBENHAM;Matthew LOMBARDO;Brent R. WHITEHEAD;Ashwin RAO;Zhicai WU;Ping LAN;Jerry A. TA
发明人:
Ashwin U. Rao,Brian Alexander McKittrick,Matthew Lombardo,Jacqueline D. Hicks,Amy Bittner McCracken,Hong Dong Chu,Sung-Sau So,Peter Orth,Zhicai Wu,Ping Lan,John S. Debenham,Brent R. Whitehead,Jerry A.
申请号：
US16461849
公开号：
US20190352294A1
申请日:
2017.11.13
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIIa inhibitors.
