A system and method for interactive processing of ECG data are presented. An electrocardiogram is displayed. A user selection of a portion of the displayed ECG is received. Digitized signals corresponding to the selection are obtained. A list of digital filters for filtering the selection are displayed. A user selection of one or more sets of the digital filters is received, with each of the sets including one or more of the filters from the list. The selected sets are applied to the digitized signals for the selection. A filtered ECG for the selection is generated for each of the sets based on the signals filtered by that set. The filtered selection ECG for each of the sets are presented on the display.