A system and method for acquiring and processing uterine EMG signals from a maternal patient. Raw uterine EMG signals are acquired and processed in a central unit designed to isolate the patient and any internal circuitry from electrical shock. The central unit has a circuit board that amplifies and filters the EMG signal, then transmits the signal to an AID converter, after which the digitized signal is transmitted to a computer for further processing of the signal and subsequent display of a signal representative of uterine activity. The system and method provide a more accurate measurement of uterine EMG signals than a tocodynamometer or IUPC, and are useful in predicting delivery or monitoring the patient during post partum uterine activity.