GIOVANNONE, DANIELE,MIRAGLIA, NICCOLO,BERNA, MARCO
申请号：
CA2929426
公开号：
CA2929426A1
申请日:
2014.11.06
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to a slow-release solid oral nutraceutical and/or pharmaceutical composition comprising: c) a core containing a donor of methyl groups and at least one pharmaceutically acceptable excipient, and d) an outer coating containing shellac and/or a pharmaceutically acceptable salt thereof, magnesium stearate, and at least one pharmaceutically acceptable excipient. The coating of said solid oral composition allows the donor of methyl groups, preferably SAMe and/or a pharmaceutically acceptable salt thereof, to cross intact the gastric barrier and release the same in a continuous and complete manner along the entire digestive tract.
