Dina Brady ANDERSON,Gavin Stephen HACKETT,Sai Man LIU
申请号：
US16800109
公开号：
US20200291073A1
申请日:
2020.02.25
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Method for preventing or treating a condition or disease in a subject comprising administering to the subject an engineered clostridial toxin comprising at least one amino acid modification that increases the isoelectric point of the toxin to a value that is at least 0.2 pI units higher than the isoelectric point of an otherwise identical clostridial toxin lacking the modification.
