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"SUPERCRITICAL PROCESSED STARCH NANOSPONGE FOR DISSOLUTION ENHANCEMENT AND FLOW PROPERTIES IMPROVEMENT OF POORLY WATER SOLUBLE AND FLOWABLE DRUGS"
专利权人:
发明人:
VAVIA PRADEEP RATILAL,JADHAV NITIN VITTHALRAO
申请号:
IN2071/MUM/2014
公开号:
IN2014MU02071A
申请日:
2014.06.26
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention includes preparation of high surface area starch nanosponges material as a carrier for dissolution enhancement and improve flow properties of model drugs. The starch nanosponge is prepared by sol-gel method (Aquagel - Alcogel - Supercritical Drying). Drug loading is achieved by solvent immersion technique. The prepared starch nanosponge material may have high surface area (upto 200 m /gm), nanopores with non-cohesive nature and particle with uniform shape. So these characteristics will be helpful to enhance the dissolution and flow properties. The present starch nanosponge carrier based system can be efficient, economical and non toxic for safe usage.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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