ÉNANTIOMÈRE D'ACIDE PHÉNYLPROPIONIQUE SUBSTITUÉ, PROCÉDÉ DE FABRICATION, COMPOSITION ET APPLICATION DE CELUI-CI

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专利权人:

Shenzhen Chipscreen Biosciences Co.; Ltd.

发明人:

申请号：

EP17854878.0

公开号：

EP3521275A1

申请日:

2017.09.27

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The present invention discloses an enantiomeric compound (-)-2- [(2-(4-fluorobenzoyl)phenyl)amine] -3 - [(4-(2-carbazole-ethoxy)phenyl)]propionic acid as represented by formula (I), or a pharmaceutical salt thereof, and a manufacturing method of the compound and application of same. The enantiomeric compound demonstrates relatively better activation of RXR/PPAR-, RXR/PPAR- and RXR/PPAR-heterodimer expression and sugar reduction in a db/db mouse model compared to a (+)-enantiomer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/