ENANTIOMERE D'ACIDE PHENYLPROPIONIQUE SUBSTITUE, PROCEDE DE FABRICATION, COMPOSITION ET APPLICATION DE CELUI-CI

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专利权人:

LTD.;SHENZHEN CHIPSCREEN BIOSCIENCES CO.

发明人:

YU, JINDI,PAN, DESI,SHAN, SONG,LI, ZHIBIN,LU, XIANPING

申请号：

CA3038382

公开号：

CA3038382A1

申请日:

2017.09.27

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present invention discloses an enantiomeric compound (-)-2-[(2-(4-fluorobenzoyl)phenyl)amine]-3-[(4-(2-carbazole-ethoxy)phenyl)]propionic acid as represented by formula (I), or a pharmaceutical salt thereof, and a manufacturing method of the compound and application of same. The enantiomeric compound demonstrates relatively better activation of RXR/PPAR-, RXR/PPAR- and RXR/PPAR-heterodimer expression and sugar reduction in a db/db mouse model compared to a (+)-enantiomer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/