WASHINGTON UNIVERSITY, ST. LOUIS;UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;AMBRUS, JULIAN, L., JR.;FAUCI, ANTHONY, S.;FORD, RICHARD, J.
发明人:
AMBRUS, JULIAN, L., JR.,FAUCI, ANTHONY, S.,FORD, RICHARD, J.
申请号:
WO1994US01101
公开号:
WO9416074(A2)
申请日:
1994.01.18
申请国别(地区):
世界知识产权组织国际局
年份:
1994
代理人:
摘要:
A mammalian high molecular weight B-cell growth factor nucleotide has been cloned and sequenced. Recombinant vectors and cells are described. Methods of providing isolated high molecular weight B-cell growth factor DNA and polypeptide sequences are disclosed, as well as methods of making transgenic animals containing or lacking the high molecular weight B-cell growth factor sequence. Clinical uses of HMW-BCGF and conjugates thereof are also described.