PROBLEM TO BE SOLVED: To provide a nicotine-containing transdermal absorption preparation having good adhesiveness and cohesion and simultaneously achieving low irritation to the skin during peeling off and a fine feeling during adhesion.SOLUTION: The nicotine-containing transdermal absorption preparation includes an adhesive layer containing a free base nicotine and a liquid ingredient compatible with the adhesive, wherein the adhesive layer is crosslinked, and the liquid ingredient is contained in a proportion of 20-75 parts by weight, per 100 parts by weight of the adhesive layer as a whole.COPYRIGHT: (C)2007,JPO&INPIT【課題】良好な粘着性と凝集力を有し、剥離時の皮膚への低刺激性と良好な貼付感が両立されたニコチン含有経皮吸収製剤を提供すること。【解決手段】粘着剤層にニコチンフリー塩基及び粘着剤と相溶しうる液状成分を含み、粘着剤層が架橋処理されており、該液状成分が粘着剤層全体100重量部に対し20~75重量部含まれていることを特徴とするニコチン含有経皮吸収製剤。【選択図】なし