STORER, ROBERT IAN,SWAIN, NIGEL ALAN,OWEN, ROBERT MCKENZIE
申请号：
TW103111102
公开号：
TW201512171A
申请日:
2014.03.25
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to new sulfonamide URAT-1 inhibitors of formula (I): or pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined in the description. URAT-1 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly gout.本發明係關於磺醯胺衍生物、其於藥物中之用途、包含其之組合物、其製備方法及用於該等方法中之中間物。更特定言之，本發明係關於新穎的式(I)之磺醯胺URAT-1抑制劑；□或其醫藥上可接受之鹽，其中R1、R2、R3、R4、R5及R6係如本發明中所定義。URAT-1抑制劑潛在性地適用於治療寬廣範圍之疾病(特別是痛風)。
