GROSU ELENA,GROSU ELENA,FICAI ANTON,FICAI ANTON,CHIFIRIUC MARIANA CARMEN,CHIFIRIUC MARIANA CARMEN,RAPA MARIA,RAPA MARIA,ULINICI SORIN CLAUDIU,ULINICI SORIN CLAUDIU,FICAI DENISA,FICAI DENISA,DITU LIA M
申请号：
RO201500105
公开号：
RO131309A2
申请日:
2015.02.16
申请国别(地区):
RO
年份:
2016
代理人:
摘要：
The invention relates to a prosthetic device with antimicrobial properties to be used in the field of medicine and to a process for making the same. According to the invention, the device is a tubing having an internal diameter of 4...32 mm and a thickness of 0.5...1.5 mm, consisting of two superposed layers (1 and 2), namely an external layer and an internal one, respectively, made of compositions based on polyvinyl chloride plasticized with tributyl-2-acetylcitrate, where the external layer (1) has an antibacterial additive content and a thickness of 0.1...0.7 mm. The process, as claimed by the invention, consists in preparing two compositions, A and B, by mixing the medical-grade polyvinyl chloride with medical-grade stabilizers, a processing additive, such as an acrylate, tributyl-2-acetylcitrate plasticizer and an epoxy soya-oil lubricant, where the composition A comprises silver nanoparticles having sizes of 2...20 nm, encapsulated in ceramic material, the compositions being processed as threads, by feeding them to extruders in which they are brought to the state of melt, at a temperature of 158...170°C, after which they are conveyed through a tubing co-extrusion nozzle, to result in a tubing made of two layers, where the external layer has antimicrobial properties.Invenţia se referă la un dispozitiv protetic cu proprietăţi antimicrobiene, şi la un procedeu pentru obţinerea acestuia, utilizat în domeniul medicinii. Dispozitivul conform invenţiei este o tubulatură având un diametru interior de 4...32 mm şi o grosime de 0,5...1,5 mm, compusă din două straturi suprapuse (1 şi 2), exterior, respectiv, interior, realizate din recepturi pe bază de policlorură de vinil plastifiat cu tributil 2-acetilcitrat, stratul (1) exterior având conţinut de aditiv antibacterian şi o grosime de 0,1...0,7 mm. Procedeul conform invenţiei constă în realizarea a două recepturi A şi B din amestecarea policlorurii de vinil de uz medical, cu stabilizatori de uz medical, un aditiv de pre
