Carole L. Cramer,Maureen C. Dolan,Giuliana Medrano,David N. Radin
申请号:
US12574598
公开号:
US08431774B1
申请日:
2009.10.06
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention is a plant-based production of biologically active avian interleukin-12 protein and functional units for increasing the protective and/or immunological response in an animal, for use as an adjuvant with a vaccine to control avian infectious diseases, and methods of producing and using the same. Specifically, avian interleukin-12 was produced from a plant-based expression system and demonstrated that it stimulates production of immune responses in birds.