Hartounian, Hartoun,Meissner, Dagmar,Pepper, Clint B.
申请号:
AU2012203661
公开号:
AU2012203661A1
申请日:
2012.06.22
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2012203661A120120712.pdf#####ABSTRACT Multivesicular liposomes are prepared at commercial scales by combining a first w/o emulsion with a second aqueous solution to form a w/o/w emulsion using a static mixer. Solvent is removed from the resulting emulsion to form multivesicular liposome-containing compositions. Further optional process steps include primary filtration and secondary cross-flow filtration. The products produced according to the processes of the invention can be produced through a series of aseptic steps.