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PREPARATION OF MULTIVESICULAR LIPOSOMES
专利权人:
PACIRA PHARMACEUTICALS; INC.
发明人:
HARTOUNIAN, HARTOUN,MEISSNER, DAGMAR,PEPPER, CLINT
申请号:
AT98957937
公开号:
AT554748T
申请日:
1998.11.13
申请国别(地区):
AT
年份:
2012
代理人:
摘要:
Multivesicular liposomes are prepared at commercial scales by combining a first w/o emulsion with a second aqueous solution to form a w/o/w emulsion using a static mixer. Solvent is removed from the resulting emulsion to form multivesicular liposome-containing compositions. Further optional process steps include primary filtration and secondary cross-flow filtration. The products produced according to the processes of the invention can be produced through a series of aseptic steps.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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