FRANC VRECER,ANDREJ FERLAN,ANDREJKA KRAMAR,URSKA TURK,LIDIA CERNOSA,MARJANCA BREZNIK,GREGOR RITLOP
申请号:
PT06764269
公开号:
PT1909761T
申请日:
2006.07.29
申请国别(地区):
PT
年份:
2017
代理人:
摘要:
Pharmaceutical composition comprising pantoprazole as the active ingredient. The pantoprazole is present in the form of particles having an average particle size within the range of 60 ¼m to 250 ¼m. Pantoprazole having an average particle size within the range of 60 ¼m to 250 ¼m is prepared by a process comprising the steps of wetting pantoprazole with water having a pH of 10 to 12 in a high shear mixer, passing the wet pantoprazole through a sieve having a mesh size of 0.8 to 2 mm, and drying the mass in a fluid bed dryer.