Chiral arylketones in the treatment of neutrophil-dependent inflammatory diseases

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专利权人:

Marcello Allegretti;Maria Candida Cesta;Cinzia Bizzarri;Riccardo Bertini;Francesco Colotta

发明人:

Marcello Allegretti,Riccardo Bertini,Maria Candida Cesta,Cinzia Bizzarri,Francesco Colotta

申请号：

US12327767

公开号：

US09328057B2

申请日:

2008.12.03

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The compounds of formula (I):where Ar is an aromatic ring and Ra, Rb, are as defined in the description, are useful in therapy as drugs for the treatment of diseases mediated by infiltrations of neutrophils induced by IL-8, such as psoriasis, rheumatoid arthritis, ulcerative cholitis and for the treatment of damages caused by ischemia and reperfusion.

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中国工程科技知识中心

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http://www.ckcest.cn/home/