MENET CHRISTEL JEANNE MARIE,HODGES ALASTAIR JAMES,VATER HUW DAVID
申请号：
NZ61752812
公开号：
NZ617528A
申请日:
2012.04.26
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
The disclosure relates to the compound N-4-(3-fluoro-4-((4-(methylsulfonyl)piperazin-1-yl)methyl)phenyl)pyrazolo[1,5-a]pyridin-2-yl)acetamide (I) and pharmaceutical compositions comprising it. The disclosure also relates to the use of this compound for treatment or prophylaxis of allergy, inflammatory conditions, autoimmune diseases, proliferative diseases, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons. The autoimmune disease may be COPD, asthma, systemic lupus erythematosis, type I diabetes mellitus, psoriatic arthritis, ankylosing spondylitis, juvenile ideopathic arthritis, and inflammatory bowel disease and the inflammatory disease may be rheumatoid arthritis, osteoarthritis, asthma and inflammatory bowel diseases.
