COMPOSITIONS METHODS AND USES FOR THERMALLY STABLE HUMAN PAPILLOMAVIRUS FORMULATIONS

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专利权人:

发明人:

RANDOLPH THEODORE,GARCEA ROBERT,HASSETT KIMBERLY J

申请号：

IN201617041262

公开号：

IN201617041262A

申请日:

2016.12.02

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

Embodiments of the present invention provide for novel compositions and methods for making and using a thermally stable human papilloma virus (HPV) formulation or other stabilized multimeric virus formulation. Certain embodiments concern lyophilizing HPV formulations in the presence or absence of adjuvants. Other embodiments concern lypophilizing HPV capsomere vaccines in order to increase stability of an immunogenic composition against HPV infection for storage delivery and use. In yet other embodiments a single immunogenic composition can include a thermally stable formulation of multiple virus serotypes.

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