Sumana CHAKRAVARTY;Stephen L. HOFFMAN;Moriya TSUJI
发明人:
Sumana CHAKRAVARTY,Stephen L. HOFFMAN,Moriya TSUJI
申请号：
US13470128
公开号：
US20120288525A1
申请日:
2012.05.11
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed herein are pharmaceutical compositions comprising Plasmodium sporozoite-stage parasites and compatible glycolipid adjuvants useful in vaccines for preventing or reducing the risk of malaria. In particular, human host range Plasmodium and analogues of α-galactosylceramide (α-GalCer), a ligand for natural killer T (NKT) cells, are combined in pharmaceutical compositions, which are useful as vaccines against malaria. Methods of use are also provided.
