An endoscope includes: an image pickup device mounted in a distal end portion of an insertion portion wiring that transmits a power supply having a plurality of different power supply voltages for driving the image pickup device, a drive signal that drives the image pickup device, an image pickup signal that is outputted from the image pickup device, and a ground level a substrate on which a connector that relays the wiring is provided a first voltage comparing portion that compares the plurality of different power supply voltages a power supply generation portion that generates a plurality of second power supply voltages a second voltage comparing portion that compares the plurality of second power supply voltages and a power supply control portion that controls a supply of power to the image pickup device based on comparison results of the first and second voltage comparing portions.