An endoscope is provided that includes: an image pickup device mounted in a distal end portion of an insertion portion wiring that transmits a power supply having a plurality of different power supply voltages for driving the image pickup device, a drive signal that drives the image pickup device, an image pickup signal that is outputted from the image pickup device that is driven by the drive signal, and a ground level a substrate on which a connector that relays the wiring is provided a voltage comparing portion that compares the plurality of different power supply voltages and power supply control means that controls a supply of power to the image pickup device based on a comparison result of the voltage comparing portion.内視鏡は、挿入部の先端部に搭載された撮像素子と、撮像素子を駆動するための複数の異なる電源電圧を有する電源、撮像素子を駆動する駆動信号、駆動信号で駆動された撮像素子から出力される撮像信号、及びグラウンドレベルを伝達する配線と、配線を中継するコネクタを設けた基板と、複数の異なる電源電圧を比較する電圧比較部と、電圧比較部の比較結果に基づき、撮像素子への電源供給を制御する電源供給制御手段と、を備える。