NOHA MOHAMED ZAKI RAYAD,IBRAHIM MAGHRABI,MOHAMED MOSTAFA HAFEZ MAHMOUD
申请号：
US14521438
公开号：
US20150044147A1
申请日:
2014.10.22
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The composition for management of periodontal diseases includes a gel matrix having a polymer system and a plurality of microspheres dispersed in the polymer system. The polymer system contains about one-half a dose of medicament, while the microspheres contain the remainder. Upon administration of the composition into the periodontal cavity, the medicament in the polymer system provides an initial therapeutic benefit, while the remainder of the medication is released over time via degradation of the microspheres. This biphasic pattern of medicament delivery provides increased efficacy of the medicament through sustained delivery of the same.
