HSA-free formulations of interferon-beta

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专利权人:

发明人:

申请号：

EP10180630.5

公开号：

EP2283896B1

申请日:

2001.10.26

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

Stabilized pharmaceutical compositions comprising substantially monomeric interferon-beta (1FN-β) and methods useful in their preparation are provided. The compositions comprise the IFN-β solubilised in a low-ionic-strength formulation that maintains the composition at a pH of about 5.0. Methods for preparing these compositions, and for increasing solubility of IFN-β in pharmaceutical compositions, are provided.

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