The professional anthocyanidin in the plant the absorption which leads the intestinal tract of the organism is easy to offer the production method of the containing professional anthocyanidin oligomer which is quantified low-molecular, various life habit illnesses where formation and the like of the active oxygen kind which designates the containing professional anthocyanidin oligomer which is obtained as the active ingredient becomes cause, the useful health food composition and the medical supply composition are offered to remedy prevention of brain disease and prevention of aging.植物中のプロアントシアニジン類を生体の腸管を通じた吸収が容易な程度に低分子量化した含硫プロアントシアニジンオリゴマーの製造方法を提供し、得られた含硫プロアントシアニジンオリゴマーを有効成分とする活性酸素種の生成等が原因となる各種生活習慣病、脳疾病の治療・予防、老化の予防に有用な健康食品組成物及び医薬品組成物を提供する。
