Ezequiel Wexselblatt,Joshua Katzhendler,Ilana Kaspy,Gad Glaser,Roee Vidavski,Hafiz Mawasi,Sigal Ben Yehuda,Yaara Oppenheimer-Shaanan
申请号:
US13813726
公开号:
US09133231B2
申请日:
2011.08.03
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Rel proteins as a novel therapeutic agent for treating bacterial threats. More specifically, a novel class of compounds of Formula (I) as disclosed herein which possess antibacterial activity and which inhibit RelA, RelSeq or RelSpo synthetic activity or bacterial spore formation. Also, pharmaceutical compositions of such compounds and a method of combating bacteria, or treating bacterial infections, by administering to a subject in need thereof such compounds or pharmaceutical compositions.