Compositions including an isolated Bacillus species, spores or anextracellular product of B. coagulans, suitable for topical application, forinhibiting growth of yeast, fungus, bacteria or Herpes simplex virus aredisclosed. Methods of inhibiting growth of yeast, fungus, bacteria or Herpessimplex virus by topical application of compositions that include an isolatedBacillus species, spores or an extracellular product of a B. coagulans strainare disclosed.