APPLICATION DE ZL-N-91, INHIBITEUR DE PHOSPHODIESTÉRASE 4, DANS LA PRÉPARATION DE MÉDICAMENTS POUR LA PROLIFÉRATION ET LES MÉTASTASES DES CELLULES CANCÉREUSES DU POUMON
The present invention discloses uses of a novel phosphodiesterase 4 (PDE4) inhibitor ZL-n-91 in preparing drugs against lung cancer proliferation and metastasis. The mouse survival curves and in vitro cell experiments show that the PDE4 inhibitor ZL-n-91 can significantly inhibit the proliferation and metastasis of lung cancer cells, indicating that this PDE4 inhibitor ZL-n-91 can become an important target for the studies on anti-lung cancer proliferation and metastasis, to provide a basis for preparing drugs against lung cancer proliferation and metastasis, with promising prospect of development and application.