PROBLEM TO BE SOLVED: To provide a method for decellularizing an organ or a tissue with less damage by using fatty acid being surfactant different from conventional surfactant or salts thereof, a method for producing a decellularized organ or tissue by the method, and a method for producing a recellularized organ or tissue having high biocompatibility by recellularizing a decellularized organ or tissue.SOLUTION: A method for decellularizing an organ or a tissue includes a process of bringing the organ or the tissue into contact with linear or branched fatty acid having a carbon number 8 to 22, or salts thereof, and a method for producing a decellularized organ or tissue including a process of decellularizing an organ or tissue by the method.SELECTED DRAWING: NoneCOPYRIGHT: (C)2020,JPO&INPIT【課題】従来の界面活性剤とは異なる界面活性剤である脂肪酸又はその塩を用いて、損傷が少なく臓器又は組織を脱細胞化する方法、該方法により、脱細胞化臓器又は組織を製造する方法の提供。脱細胞化臓器又は組織を再細胞化することで、生体適合性が高い、再細胞化臓器又は組織を製造する方法の提供。【解決手段】臓器又は組織に、炭素数８～２２の直鎖状又は分岐鎖状の脂肪酸又はその塩を接触させる工程を含む、該臓器又は組織を脱細胞化する方法、及び該方法により臓器又は組織を脱細胞化する工程を含む、脱細胞化された臓器又は組織の製造方法。【選択図】なし
