The United States of America, as Represented by the Secretary, Department of Health and Human Serv;NOVARTIS AG
发明人:
Barbara K. FELBER,Sergio FINKIELSZTEIN,George N. PAVLAKIS,John V. VOURNAKIS
申请号：
US16291561
公开号：
US20190290734A1
申请日:
2019.03.04
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to agents that modulate interleukin-15 (“IL-15”) signal transduction or function (“Therapeutic Agents”) and the use ol” those agents to modulate immune function. The Therapeutic Agents target the interaction between IL-15 and its receptor and modulate IL-15-induced signal transduction. The Therapeutic Agents may be formulated with polymers, such as poly-β-1-♦；4-N-acetylglucosamine. for administration to a human subject to modulate IL-15-mediated immune function.
