The United States of America; as represented by the Secretary; Department of Health and Human Services
发明人:
Pavlakis, George N.,Voumakis, John N.,Felber, Barbara K.,Finkielsztein, Sergio
申请号:
AU2016206235
公开号:
AU2016206235A1
申请日:
2016.07.19
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2016206235A120160804.pdf#####H:\ft\interwoven\NRPortbl\DCC\FMT\l0507844_ .docx-18/07/2016 ABSTRACT The present invention relates to agents that modulate interleukin-15 ("IL-15") signal transduction or function ("Therapeutic Agents") and the use ol" those agents to modulate immune function. The Therapeutic Agents target the interaction between IL-15 and its receptor and modulate IL-15-induced signal transduction. The Therapeutic Agents may be formulated with polymers, such as poly-3- 1- +4-N-acetylglucosamine. for administration to a human subject to modulate IL-15-mediated immune function.