Recombinant polypeptide for enhancing cell transduction efficiency of a target agent

• 收藏
• 分享

专利权人:

Agricultural Technology Research Institute

发明人:

Chin-Kai Chuang,Yu-Hsiu Su,Tzuyin Lin

申请号：

US15380253

公开号：

US10717994B2

申请日:

2016.12.15

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The invention provides a recombinant polypeptide X—；Y for enhancing cell transduction efficiency of a target agent, wherein X is a cell penetrating peptide DPV3, and Y is an Hsp40-J domain. Also provided is a method for enhancing cell transduction efficiency of a target agent, comprising conjugating/attaching said target agent with a recombinant polypeptide X—；Y, wherein X is a cell penetrating peptide DPV3, and Y is an Hsp40-J domain. Further provided is a pharmaceutical composition comprising a therapeutic agent, wherein said therapeutic agent is modified by conjugating/attaching with a recombinant polypeptide X—；Y, wherein X is a cell penetrating peptide DPV3, and Y is an Hsp40-J domain.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/