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VIRUS-CONTAINING DRUG AND ITS USE
专利权人:
ТРАНСГЕН СА (FR)
发明人:
СЕН Клод (FR),ШАСЛЬ Мелина (FR)
申请号:
RU2015116539
公开号:
RU2015116539A
申请日:
2013.10.02
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A composition comprising (i) at least one virus-based material, (ii) at least one polymer selected in the group of polyvinylpyrrolidone and its derivatives, and a mixture thereof, (iii) at least one sugar, (iv) at least two different amino acids, (v) at least two pharmaceutically acceptable salts, wherein at least one of said salts is a phosphate salt, and optionally (vi) a pharmaceutically acceptable buffer. The composition of claim 1, wherein it is an aqueous composition. A composition according to claim 2, wherein said (ii) at least one polymer is selected in the group of polyvinylpyrrolidone and its derivatives and mixtures thereof. A composition according to claim 3, wherein said polyvinylpyrrolidone or its derivatives have a molecular weight of 10 to 40 kDa, preferably 15 to 30 kDa and more preferably 25 kDa. A composition according to claim 3, wherein said composition contains from 10 to 50 g / l, preferably from 15 to 40 g / l and more preferably from 20 to 35 g / l of polyvinylpyrrolidone or derivatives, or a mixture thereof. A composition according to claim 4, wherein said composition contains from 10 to 50 g / l, preferably from 15 g / l to 40 g / l, and more preferably from 20 to 35 g / l of polyvinylpyrrolidone or derivatives, or a mixture thereof. A composition according to claim 2, wherein said (iii) at least one sugar is selected from a monosaccharide, disaccharide, trisaccharide and tetrasaccharide, and derivatives thereof. The composition of claim 7, wherein said composition comprises at least one disaccharide selected from the group consisting of sucrose, lactulose, lactose, maltose, trehalose, cellobiose, isomaltose and maltulose. A composition according to claim 7, wherein said composition contains from 20 to 80 g / l, preferably from 30 to 70 g / l, and more preferably from 40 to 60 g / l of sugar. The composition of claim 9, wherein1. Композиция, содержащая (i) по меньшей мере один материал на основе вируса, (ii) по меньшей мере один полиме
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