The 2 of tumor formation disease, inflammation and disease of immune system are treated with what,4- pyrimidinediamines农业专利-农业学术服务平台

发明人:: C．加西亚－埃切维里亚,C．加西亞－埃切维里亞,金轮孝则,金輪孝則,河原英二,升谷敬一,松浦直子,高广三宅,高廣三宅,大森治,梅村一郎,R．斯廷斯玛,R．斯廷斯瑪,G．肖浦克,J．江,Y．万,Y．萬,丁强,丁強,Q．张,Q．張,N．S．格雷,D．卡拉纽斯基,D．卡拉紐斯基,C.加西亚-埃切维里亚,C.加西亞-埃切维里亞,R.斯廷斯玛,R.斯廷斯瑪,G.肖浦克,J.江,Y.万,Y.萬,Q.张,Q.張,N.S.格雷,D.卡拉纽斯基,D.卡拉紐斯基

摘要：: The present invention relates to the purposes of the pyrimidine derivatives of new formula (I) and these compounds in the drug that preparation treats or prevents the disease that response what FAK and/or ALK and/or ZAP-70 and/or IGF-IR inhibits with what. In formula (I), R defines identical in C6-10 aryl, C5-10 heteroaryls, C3-12 naphthenic base and C3-10 Heterocyclylalkyls, R0-R6 and specification.本發明涉及新的式(I)的嘧啶衍生物以及這些化合物在製備用於治療或預防響應於FAK和／或ALK和／或ZAP-70和／或IGF-IR抑制的疾病的藥物中的用途。在式(I)中，R選自C6-10芳基、Ｃ5-10雜芳基、C3-12環烷基和C3-10雜環烷基，R0-R6與說明書中定義相同。