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2,4-PYRIMIDINADIAMINES, THEIR USES, COMBINATION AND PHARMACEUTICAL COMPOSITION
专利权人:
NOVARTIS AG
发明人:
CARLOS GARCIA-ECHEVERRIA,DONALD KARANEWSKY,EIJI KAWAHARA,GREG CHOPIUK,ICHIRO UMEMURA,JIQING JIANG,KEIICHI MASUYA,NAOKO MATSUURA,NATHANAEL SCHIANDER GRAY,OSAMU OHMORI,QIANG DING,QIONG ZHANG,RUO STEENSM
申请号:
BR122019017579
公开号:
BR122019017579B1
申请日:
2004.08.13
申请国别(地区):
BR
年份:
2020
代理人:
摘要:
the present invention relates to pyrimidine derivatives of formula (i) in which r is selected from c16-10 aryl, c5-10 heteroaryl, c3-12 cycloalkyl and c3-10 heterocycloalkyl; r0 - r6 are as described herein; and its use for the production of a medicine for the treatment or prevention of a disease that responds to inhibition of fak and / or alk and / or zap-70 and / or igf-ir.a presente invenção se refere a derivados de pirimidina de fórmula (i) na qual r é selecionado de c16-10 arila, c5-10 heteroarila, c3-12 cicloal-quila e c3-10 heterocicloalquila; r0 - r6 são como aqui descritos; e seu uso para a produção de um medicamento para o tratamento ou a prevenção de uma doença que responde à inibição de fak e/ou alk e/ou zap-70 e/ou igf-ir.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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