THE REGENTS OF THE UNIVERSITY OF MICHIGAN;EASTERN MICHIGAN UNIVERSITY
发明人:
LAWRENCE, DANIEL A.,EMAL, CORY,REINKE, ASHLEY,LI, SHIH-HON,WARNOCK, MARK,ABERNATHY, GREGORY
申请号：
CA2888996
公开号：
CA2888996A1
申请日:
2013.10.31
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention relates to plasminogen activator- 1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or disorder associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to prevent or reduce thrombosis and fibrosis, to promote thrombolysis, and to modulate lipid metabolism and treat diseases or disorders associated with elevated PAI-1, cholesterol, or lipid levels.
