THE REGENTS OF THE UNIVERSITY OF MICHIGAN;EASTERN MICHIGAN UNIVERSITY
发明人:
Daniel A. Lawrence,Cory Emal,Ashley Reinke,Shih-Flon Li
申请号：
US16631066
公开号：
US20200147007A1
申请日:
2018.07.27
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or disorder associated with elevated PAI-1. The disclosure includes, but is not limited to, the use of such compounds to prevent or reduce thrombosis and fibrosis, to promote thrombolysis, and to modulate lipid metabolism and treat diseases or disorders associated with elevated PAI-1, cholesterol, or lipid levels.
