THE REGENTS OF THE UNIVERSITY OF MICHIGAN;EASTERN MICHIGAN UNIVERSITY
发明人:
LAWRENCE, DANIEL A.,EMAL, CORY,REINKE, ASHLEY,LI, SHIH-HON
申请号：
CA3070303
公开号：
CA3070303A1
申请日:
2018.07.27
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Provided herein are plasminogen activator-1 (PAI-1 ) inhibitor compounds anduses thereof in the treatment of anydisease or disorder associated with elevated PAI-1. The disclosure includes,but is not limited to, the use of such compounds to preventor reduce thrombosis and fibrosis, to promote thrombolysis, and to modulatelipid metabolism and treat diseases or disorders associatedwith elevated PAI-1, cholesterol, or lipid levels.
