1. Refers to a compound represented by a formula (i) or its salt, where X is -N = O-CRA=；RA is H, halogenated or C1-6 tar； ES-C(= O) - or other； Q1 is C6-10 Arilo or 5-10 member isomerization, which can be replaced by halogenated or C1-6 tar； Q2 is 3-12 member isomerization or 5-10 member isomerization, both of which can be replaced. Halogen compounds, C1-6 tar, etc. R1, R2 and R3 are hydrogen, C1-6 are tar, etc. R4, R5 and R6 are hydrogen, C1-6 are tar, R7 and R8 are hydrogen, C1-6 are tar, etc. N1 is an integer of 0 to 3, N2 is an integer of 0 to 5, R9 is a compound. Mulan (IIA),(2)These include R9A and R9B hydrogen, C1-6 tar, etc. Z1 is a formula compound (IIIA).(IIIB)Among other things, N4 is an integer from 1 to 3, N5 is an integer from 0 to 10, locking position with pyridineAnd Z2 are C1-6 tars or other substances. He also mentioned a drug synthesis, a preparation method, a preventive or therapeutic agent, including the invention of compounds or their salts. Current inventions as analgesics for type 1 glucose (GLP-1) receptors are useful for the treatment or prevention of non-insulin diabetes mellitus (type 2 diabetes).Obesity and similar diseasesSe refiere a un compuesto representado por la formula (I) o su sal, en donde: X es -N= o -CRa=； Ra es H, halogeno o C1-6 alquilo； Y es -C(=O)- u otros； Q1 es C6-10 arilo o heteroarilo de 5 a 10 miembros, estando ambos opcionalmente sustituidos con halogeno, C1-6 alquilo, entre otros； Q2 es heterociclilo de 3 a 12 miembros o heteroarilo de 5 a 10 miembros, estando ambos opcionalmente sustituidos con halogeno, C1-6 alquilo, entre otros； R1, R2 y R3 son hidrogeno, C1-6 alquilo, entre otros； R4, R5 y R6 son hidrogeno, C1-6 alquilo, entre otros； R7 y R8 son hidrogeno, C1-6 alquilo, entre otros； n1 es un numero entero entre 0 y 3； n2 es un numero entero entre 0 y 5； R9 es un compuesto de formula (IIa), (IIb), entre otros, siendo R9a y R9b hidrogeno, C1-6 alquilo, entre otros； Z1 es un compuesto de formula (IIIa), (IIIb), en
