THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMT OF HEALTH AND HUMAN SERVICES;GLG PHARMA, LLC;MRIGLOBAL
发明人:
SHOEMAKER, ROBERT H.,WHITE, JONATHAN M.,GUPTA, SHANKER,LOVELL, MICHAEL W. (DECEASED)
申请号：
CA3058973
公开号：
CA3058973A1
申请日:
2018.04.05
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Disclosed is a salt prepared from the STAT3 inhibitor known as 2-hydroxy-4-[[2-[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino] benzoic acid and 2-amino-2-(hydroxymethyl)-1,3-propanediol. The salt is soluble in water and stable for extended periods of time. Further provided are pharmaceutical compositions comprising the salt and methods of administering the salt to prevent and treat cancer, such as breast cancer.
