GLG Pharma, LLC;The United States of America, as represented by The Secretary, Department of Health and Human Services;MRIGlobal
发明人:
Gupta, Shanker,Lovell, Michael W.,Shoemaker, Robert H.,White, Jonathan M.
申请号:
AU2018248303
公开号:
AU2018248303A1
申请日:
2018.04.05
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Disclosed is a salt prepared from the STAT3 inhibitor known as 2-hydroxy-4-[[2-[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino] benzoic acid and 2-amino-2-(hydroxymethyl)-1,3-propanediol. The salt is soluble in water and stable for extended periods of time. Further provided are pharmaceutical compositions comprising the salt and methods of administering the salt to prevent and treat cancer, such as breast cancer.