The United State of America, as represented by the Secretary, Department of Health and Human Service;GLG Pharma, LLC;MRIGLobal
发明人:
Robert H. Shoemaker,Michael W. Lovell,Jonathan M. White,Shanker Gupta
申请号:
US16603110
公开号:
US20200109109A1
申请日:
2018.04.05
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed is a salt prepared from the STAT3 inhibitor known as 2-hydroxy-4-[[2-[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino] benzoic acid and 2-amino-2-(hydroxymethyl)-1,3-propanediol. The salt is soluble in water and stable for extended periods of time. Further provided are pharmaceutical compositions comprising the salt and methods of administering the salt to prevent and treat cancer, such as breast cancer.