ELGERSMA, RONALD CHRISTIAAN,HUIJBREGTS, TIJL,COUMANS, RUDY GERARDUS ELISABETH
申请号:
CA3038427
公开号:
CA3038427A1
申请日:
2017.10.11
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to linker-drug compounds (LDs) and antibody-drug conjugates (ADCs) comprising a non-linear self-immolative linker, which is cleavable or transformable under appropriate conditions and which reduces the hydrophobicity of the antibody-drug conjugate.