ELGERSMA, Ronald Christiaan,HUIJBREGTS, Tijl,COUMANS, Rudy Gerardus Elisabeth
申请号:
DK17780446
公开号:
DK3525826T3
申请日:
2017.10.11
申请国别(地区):
DK
年份:
2020
代理人:
摘要:
The present invention relates to linker-drug compounds (LDs) and antibody-drug conjugates (ADCs) comprising a non-linear self-immolative linker, which is cleavable or transformable under appropriate conditions and which reduces the hydrophobicity of the antibody-drug conjugate.